North American Registry of Midwives (NARM) Practice Exam

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How soon after birth should an infant born to an HIV infected mother begin receiving zidovudine (ZDV)?

  1. Within 6 hours

  2. Within 12 hours

  3. Within 24 hours

  4. Within 48 hours

The correct answer is: Within 12 hours

The correct response is that an infant born to an HIV-infected mother should begin receiving zidovudine (ZDV) within 12 hours of birth. This timing is crucial to significantly reduce the risk of HIV transmission from mother to child. Research demonstrates that early administration of antiretroviral therapy such as ZDV is effective in preventing vertical transmission, which is why it is emphasized to start the medication as soon as possible within that timeframe. Initiating therapy within 12 hours allows for the best possible outcome in safeguarding the infant against potential HIV infection. This prompt intervention is part of established clinical guidelines and practices aimed at minimizing the risks associated with perinatal HIV transmission.