North American Registry of Midwives (NARM) Practice Exam

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What is the most common factor indicating the need for chorionic villus sampling (CVS)?

Family history of genetic disorders
Maternal age
Previous pregnancy complications
Parental genetic testing

The correct answer is: Maternal age

The most common factor indicating the need for chorionic villus sampling (CVS) is maternal age. As women age, particularly those over 35, the risk of chromosomal abnormalities in the fetus increases, notably conditions like Down syndrome (Trisomy 21). CVS is often recommended for older mothers because it allows for earlier detection of these abnormalities compared to amniocentesis, which is typically performed later in pregnancy. While family history of genetic disorders, previous pregnancy complications, and parental genetic testing can certainly influence the decision to pursue CVS, maternal age has a well-established correlation with the risk of serious genetic conditions. Thus, it is a critical factor that often leads healthcare providers to recommend CVS as part of the prenatal screening process for older expectant mothers.