North American Registry of Midwives (NARM) Practice Exam

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Which disease risk is significantly reduced by oral contraceptives?

  1. Breast cancer

  2. Heart disease

  3. Ovarian cancer

  4. Cervical cancer

The correct answer is: Ovarian cancer

Oral contraceptives have been shown to significantly reduce the risk of ovarian cancer. This protective effect is particularly noteworthy in individuals who use oral contraceptives for multiple years. The mechanism behind this reduction is believed to be related to the suppression of ovulation; since ovarian cells are not subjected to cyclical changes and potential injury during ovulation, the overall risk of developing cancer in the ovarian tissue decreases. In contrast, while oral contraceptives can have variable effects on breast and cervical cancer risks, the strong evidence supporting the reduction in ovarian cancer incidence makes it the most relevant answer to the question. Thus, the association between long-term use of oral contraceptives and lower ovarian cancer risk is well-supported in medical literature, highlighting the significance of this preventive aspect in women's health.